【正文】
Agents for Parkinson’ s Disease 治療中樞神經(jīng)系統(tǒng)退行性疾病藥物 17 Parkinson’ s Disease( PD) : Originally described in 1817 by British physician, James Parkinson, who called it “ the shaking palsy.About 1960 the disease was traced to the loss of dopamineproducing neurons in the substantia nigra Symptoms of PD: Trembling of hands, arms, legs, jaw and face Stiffness of the arms, legs and trunk Slowness of movement Poor balance and coordination 第 1節(jié) 抗帕金森氏病藥 AntiPD Drugs 1. Mechanism of PD Dopamine: