阿拉伯糖操縱子ppt課件(完整版)
【正文】 A loop. ? This structure causes repression of transcription of the araBAD genes. Arabinose Operon ? 1. Coordinated expression of Arabinose Isomerase, ribulokinase, and an epimerase in response to arabinose diet in E. Coli in absence of glucose. (Ara A, Ara B, Ara D). ? Gene anization deduced from geics. Two operators (Ara O1 and Ara O2) control expression of the BAD genes. ? 2. Ara C codes for a protein (Cprotein) which mediates repression of BAD expression by binding to Ara O2. ? 3. CProtein also represses its own synthesis at low concentrations of cAMP and represses BAD expression unless arabinose is present. ? a. CProtein footprint at three sites (Ara O1, Ara O2, and Ara I) in absence of aribinose and presence of glucose (low cAMP). ? 4. However geicall
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