人工血管(及組織工程)-文庫吧在線文庫
【正文】 eedimensional electrospun polyurethane vascular grafts micropatterned, smalldiameter polyurethane grafts capable of promoting the formation of aligned endothelial cell monolayers. Pimpon Uttayarat, Peter I. Lelkes et al. Acta Biomaterialia, 2023, 6, 4229–4237 無支架 人工血管 Human umbilical vein SMCs and skin fibroblasts were cultured for ～ 30 days, at which time both cell types had formed cohesive cellular sheets posed of cells and ECM, which could be manually peeled from the culture flasks. John D. Kakisis, Athens. Greece. et al. Journal of Vascular Surgery, 2023, 41, 349354. Sumpio BE. Austin, TX: RG Landes Publishers, 1993, . 類模具法人工血管 John D. Kakisis, Athens. Greece. et al. Journal of Vascular Surgery, 2023, 41, 349354. N. L’Heureux, L. Germain, R. Labbe, . Auger. J Vasc Surg, 1993, 17, 499509 The inner surface of the graft was seeded with bovine ECs and the outer with bovine adventitial fibroblasts. A Dacron mesh was embedded into the wall to enhance the mechanical strength of the model. 無支架細(xì)胞操控 Morphological and Histological Evaluations of 3DLayered Blood Vessel Constructs Prepared by Hierarchical Cell Manipulation Michiya Matsusaki, Mitsuru Akashi et al. Journal of Biomaterials Science, 2023, 23, 63–79 總結(jié)與展望 血管生物支架 存在強(qiáng)烈的免疫排斥反應(yīng)也是需要解決的一個(gè)難題人工合成材料的優(yōu)點(diǎn)是強(qiáng)度、降解速度、微結(jié)構(gòu)和滲透性均可在生產(chǎn)過程中進(jìn)行控制；而天然材料的優(yōu)點(diǎn)則在于包含有生物信息 ( 如特殊的氨基酸序列 ) ，可促進(jìn)細(xì)胞吸附或使細(xì)胞保留分化功能。隨后， Pittenger等證實(shí)了骨髓間充質(zhì)干細(xì)胞不僅具有分化成血管平滑肌細(xì)胞，并參與平滑肌細(xì)胞重建。 分類 具體內(nèi)容 天然生物支架材料 甲殼素、葡聚糖明膠、膠原蛋白、彈性蛋白、多聚氨基酸、多肽、透明質(zhì)酸及其復(fù)合物等 去細(xì)胞生物源
醫(yī)療健康相關(guān)推薦
鄂ICP備17016276號(hào)-1