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錐蟲(trypanosoma)表面抗原轉(zhuǎn)換機(jī)制-全文預(yù)覽

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【正文】 ) ,說明變體出現(xiàn)是有順序的(與同源性有關(guān));但也有人認(rèn)為是隨機(jī)產(chǎn)生的。因?yàn)榭贵w存在,產(chǎn)生免疫清除反應(yīng),加速了 VSG的替換和變體產(chǎn)生速度。 謝 謝 ! Fig1. Minichromosomes (red) and large chromosomes (yellow) exhibit different positional dynamics during mitosis. DNA(blue) Fig2: Schematic representation of a trypanosomal variant surface glycoprotein(VSG) gene expression after Revelard et Lips et flag indicates the promoter ,the number in the box indicate the expression siteassociated genes (ESAGs), V indicates the VSG gene,and End indicates the chromosome enlargements show feature of ESAG6 and ESAG7,which encode subunits of the TfR. Fig2: Schematic representation of a trypanosomal variant surface glycoprotein(VSG
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