rds-hie-ivh－全英班-全文預覽
【正文】 st choice) loading dose 1520mg/kg IV maintenance dose 35mg/kg/d ? Diazepam（ 安定 〕 ? Chloral hydrate 49 TreatmentIII of cerebral edema ? Frusemide (first choice) ? Albumin ? Mannitol 50 Intracranial hemorrhage of the newborn 51 ? remains a significant cause of both morbidity and mortality in infants born prematurely. ? Sequelae include lifelong neurological deficits, such as cerebral palsy, developmental delay, and seizures. ? PVHIVH remains a serious problem for preterm infant Intracranial hemorrhage of the newborn 52 Etiology and pathogenesis 1. Vascular factor 32wk premature infant ? immature blood vessels in germinal matrix (subependymal region) ? perinatal hypoxia and blood pressure fluctuations ? subependymal hemorrhage(SEH) ? periventricular – intraventricular hemorrhage (PVHIVH) 53 Where is germinal matrix ? 54 腦室室管膜下生發(fā)層的分布 55 Etiology and pathogenesis factor Hypoxia, acidosis, wide fluctuation of cerebral blood flow velocity ? impairment of vascular autoregulation ? “pressure passive circulatory state” ? capillary injury 56 Etiology and pathogenesis trauma Laceration of tentorium cerebelli,falx cerebri and cerebral superficial vein ? Rupture of cerebral vein ? Subdural hemorrhage(SDH) 57 Subdural hemorrhage (SDH) 58 硬腦膜竇圖解 (矢狀面 ) 59 Etiology and pathogenesis 4. Other factors ? Vit k deficiency, coagulopathy ? Maternal ITP ? Maternal medication (phen
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