volumetric automatic breast density assessment in an …：容量自動(dòng)乳腺密度評(píng)估一…-全文預(yù)覽
【正文】 in XIPBuilder Dense Tissue Volume Total Tissue Volume x 100 = Percent Density RADBuilder Process S o X I P L o a dD I C O MS o I t k B in a r yT h r e s h o ldI m a g e F ilt e rS o X I P B r e a s tT o t a lT is s u eV o lu m eC a lc u la t io nS o I t k M u lt ip lyI m a g e F ilt e rS o X I P B r e a s tD e n s eT is s u e V o lu m eC a lc u la t io nS o X I P L in e a rA t t e n u a t io nC o e f f ic ie n t sC a lc u la t o r S e p a r a t o rS o I t k B in a r yT h r e s h o ldI m a g e F ilt e rSeparator ? Module in RADBuilder ? Displays output ? In this case, text Methods II ? 20 CC fullfield digital mammograms ? Prior manual breast density assessment using ImageJ ? Determine breast density using Cumulus?, a popular interactive thresholding program ? Determine breast density with the automated XIP solution Methods III ? Compare the three measurements of breast density to determine Kendall’s Coefficient of Concordance ? Use that coefficient to determine a χ2 that allows testing of the null hypothesis: There is no agreement in the assessment of breast density by the three methods Results ? The overall Kendall’s Coefficient paring the three systems was ? For 20 cases and three systems, the χ2 is which allows the rejection of the null hypothesis (χ2 of , 19 degrees of freedom, α =). Conclusion ? It was possible to develop, in XIP, an automatic software application to measure volumetric breast density in mammograms. ? The automatic measurement agreed well with two, independent, manual thresholding based techniques in mon, current use. Future Work ? MLO view capability ? Anisotropic Filter ? Improve fatty reference value identification ? Validate this and other techniques against ground truth (MRI) References 1. Boyd, N., Lockwood, G., Byng, J., Tritchler, D., Yaffe, M., “Mammographic Densities and Breast Cancer Risk”. Cancer Epidemiology, Biomarkers amp。d, eff 181。d, eff 181。Automatic Volumetric Breast Density Assessment in the eXtensible Imaging Platform Rachel Embree and Christina Sillery David Channin, MD, Advisor In Cooperation with Alex Shnayder, Pat Mongkolwat, Ray Wu Overview ? Introduction ? Material and Methods ? Results ? Discussion ? Conclusion Introduction What is Breast Density? ? The breast is posed of fibroglandular tissue embedded in a background of fatty tissue. The amount of fibroglandular tissue and fat varies among women. ? Breast cancer arises in this fibroglandular tissue. ? Mammography is projection radiography of the breast. ? In mammograms, dense fibroglandular tissue attenuates more radiation than does fat. ? Breast density refe
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