susceptibilityofcemcellclonestogc-evokedapoptosiscem細胞克隆誘發(fā)細胞凋亡的gc敏感性(已修改)
2025-01-24 08:36 本頁面
【正文】 ROLE OF INTRACELLULAR CALCIUM IN GLUCOCORTICOIDEVOKED LYMPHOID CELL APOPTOSIS Devin Morris California State University, Northridge Apoptosis Release of cyctochrome c Effector Caspases Apoptosis Stimuli/ Death signals Apoptosome formation Activation of caspase cascade Apaf1 Caspase 9 Proliferation Cell Population Cell Death ? Development ? Homeostasis ? Disease Physiological roles of apoptosis R IPC ABC IPC R IPC R R R R R ligand receptor interacting proteins coactivator plex basal trans. factors 1 2 3 4 Glucocorticoid Pathway Susceptibility of CEM Cell Clones to GCEvoked Apoptosis GCinduced Increase in Intracellular Calcium in GCSusceptible CEM cells Time amp。 GCDoseDependent Increase in [Ca+2]i
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